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diagnosis differential management signs symptoms hematology treatment cardiology neurology pathophysiology syndrome classification comparison dermatology lupus systemic algorithm erythematosus sle vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Night sweats • Arthralgias ... purpura: Strong sign ... pulse deficits vascular ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad: Fever ... , Arthralgia/arthritis ... abnormalities • Muscular ... management #treatment #rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
Onset Still's Disease ... criteria: - Fever ... = 1 weeks - Arthralgia ... with concomitant fever ... #Major #Minor #Rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
platelet disorders, vascular ... Etiology: • Vascular ... Disruptions in vascular ... mountain spotted fever ... #rheumatology #
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic Fever ... inflammation • Fever ... • Arthralgia ... Pancarditis and valvular ... pathophysiology #diagnosis #signs
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
• Rickettsial diseases ... • Crohn disease ... • Behcet disease ... Non-Infectious Causes ... Brucellosis Faget's Sign
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Insufficiency Addison's Disease ... Lymphoma Metastatic Disease ... • Low-grade fever ... Back pain • Arthralgia ... Reduced libido • Signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Deposition - Arthralgia ... trabecular thinning -> Avascular ... Myopathy (Also caused ... pathophysiology #signs
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
Lyme Disease: Early ... Fatigue, myalgia, arthralgia ... , headache, fever ... WuidQ #Lyme #Disease ... #diagnosis #signs
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Vascular System ... TeIangiectasia Vascular ... Diagnosis #Algorithm #Causes ... #Hematology
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