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diagnosis hematology algorithm classification management oncology syndrome cardiology emesis ncpe noncardiogenic platelets pulmonary rheumatology vomiting acidosis anasarca apml approach blood
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Reactive: • Anemia ... • Infection/Sepsis ... Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... ): • Acute infection ... malignancies • Anemia ... #hematology #secondary
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Infectious: • Acute ... Iron deficiency anemia ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... Platelet Count - Differential ... → Refer to hematology ... hemolysis, deficiency anemia ... #Platelets #Differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Normal RBCs • Acute ... #Differential # ... #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm Acute ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology ... #Markers #Differential
Causes of Generalized Edema - Differential Diagnosis Algorithm Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... Edema - Differential ... Inflammation • Sepsis ... • Acute Respiratory ... Burns/Trauma #Edema
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Blood Loss • Acute ... Classification #Approach #Differential ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Peripheral Edema - Differential Diagnosis Increased Hydrostatic Pressure • Volume Expansion: Kidney failure, Pregnancy, Medication
Causes of Peripheral ... Edema - Differential ... prednisone, NSAIDs), Acute ... Permeability: Sepsis ... #Differential #
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... kidney disease, Acute ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
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