22 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... TTP/HUS indicates ... purpura/hemolytic ... , Hematology 2012 ... #Diagnosis #Differential
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... HemolyticUremicSyndrome #HUS ... #thrombocytopenia ... Comparison #Diagnosis #Table ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... uremic syndrome (HUS ... #differential # ... diagnosis #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... • Thrombotic Thrombocytopenic ... Microangiopathy #TMA #hematology ... #differential #
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential ... MAHA (TTP, DIC, HUS ... Extravascular #Differential ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Schistocytes, thrombocytopenia ... DIC, TTP, HELLP, HUS ... #Anemia #Differential ... Algorithm #workup #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... - Bacterial: Sepsis ... Microangiopathy: DIC, TTP, HUS ... #Differential #
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Syndrome • TTP/HUS ... #Differential # ... #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • MAHA: TTP, HUS ... #Anemia #Differential ... classification #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Pregnancy - TTP/HUS ... defects. 1) HELLP (Hemolysis ... child * Severe cases ... #diagnosis #table