24 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... Often hard to differentiate ... #thrombocytopenia ... Comparison #Diagnosis #Table ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... Thrombocytopenic ... Microangiopathy #TMA #hematology ... #differential #
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... TTP/HUS indicates ... thrombotic thrombocytopenic ... , Hematology 2012 ... #Diagnosis #Differential
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... - Bacterial: Sepsis ... Microangiopathy: DIC, TTP, HUS ... #Differential #
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Syndrome • TTP/HUS ... #Differential # ... #Hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... - Differential ... artery aneurysm: Causes ... - MAHA: TTP, HUS ... #Differential #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... Treat primary cause ... Coagulation #diagnosis #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic ... uremic syndrome (HUS ... #differential # ... diagnosis #hematology
Underlying causes of PEA arrest: H’s and T’s 

Hypovolemia, Hypoxia, Hydrogen Ion (acidosis), Hypo/Hyper-kalemia, Hypothermia
Toxins, Tamponade,
Underlying causes ... of PEA arrest: H’ ... Pneumothorax, Thrombosis ... #arrest #HsTs #Differential ... #Diagnosis #Table
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... almost) all TMAs cause ... triad of MAHA + thrombocytopenia ... @AnnKumfer #Thrombotic ... Microangiopathy #TMAs #hematology