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management differential algorithm oncology anemia syndrome comparison workup classification disease lupus thrombocytopenia autoimmune dermatology hemolysis sle vasculitis blood cold disorders
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... fragmentation hemolysis ... Catastrophic APLS BCM ... #differential #diagnosis ... #hematology #hemolysis
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... 2) LOOK FOR a cause ... #Anemia #diagnosis ... #management #treatment ... #rheumatology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Differential #Causes ... #Workup #Hematology ... #Diagnosis *
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... - Differential Diagnosis ... Sophia_Hayes_MD #Hemolytic ... #Differential #Diagnosis ... #Causes #hematology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Cold Autoimmune Hemolytic ... Spherocytes • Treatment ... • Treatment: Warm ... #Anemia #hematology ... #diagnosis #comparison
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... - Differential Diagnosis ... Table Warm AIHA ... #Autoimmune #Hemolytic ... #Table #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Extravascular #Causes ... #differential #diagnosis ... #hematology #anemia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Artifact (redo CBC ... effect following treatment ... #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... #Algorithm #hematology
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