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diagnosis nephrology differential injury kidney renal calcium cancer causes classification deposition diuretics excretion framework hematology hepatology hepatorenal hrs hyperkalemia hyperphosphatemia
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... LC deposition disease ... Minimal change disease ... malignancies Treatment ... Interleukin-2) • Tumor lysis
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
t-PA, heparin Acute ... Rhabdomyolysis, Tumor lysis ... syndrome, Hemolysis ... acidosis, DKA Kidney Disease ... : • AKI, CKD
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
• Triggers: Diuretics ... have fever - ACS ... , AKI, acute limb ... organ damage • Treatment ... #diagnosis #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Torsemide) • Acute ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... high preload → Diuretics ... • Hepatorenal syndrome ... #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis ... , RTA Type IV, AI ... reabsorption) Workup ... acidosis), CK+LDH (lysis ... #nephrology #K
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Acute CPP Crystal ... Pseudogout: Treatment ... CPPD disease ... Crowned Dens Syndrome ... Rheumatology #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... + myoglobin AKI ... disease 2. ... Loop diuretics for ... #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... EGPA) • Renal: (AKI ... mononeuritis multiplex WORKUP ... differential #diagnosis #management ... #treatment
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... advanced liver disease ... hepatitis, or acute ... Treatment Overview ... #Hepatorenal #Syndrome
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