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hematology causes anemia management workup diarrhea thrombocytosis mcv pruritus secondary atlas chronic classification dermatology elevatedmcv endocrinology erythrocytosis generalized hemolytic hypocalcemia
Polycythemia vera, Essential thrombocythemia, Primary myelofibrosis Diagnosis Algorithm • Polycythemia vera → Blood JAK2 mutation screening
Polycythemia vera ... Algorithm • Polycythemia ... vera → Blood JAK2 ... cytogenetics #hematology ... #PV #ET #diagnosis
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Differential Diagnosis ... Cardiac/pulmonary disease ... #Vera #PV #Differential ... #Diagnosis #Algorithm ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... specifically: iron deficiency ... thrombocythemia (ET) • Polycythemia ... vera (PV) • Myelodysplastic ... #hematology #secondary
Causes of Pediatric Diarrhea - Differential Diagnosis Algorithm Infectious: • Viral • Bacterial • Parasitic Malabsorption: • Lactase
- Differential ... Diagnosis Algorithm ... Fibrosis • Celiac Disease ... #Differential # ... Diagnosis #Algorithm
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Diagnosis Algorithm ... bcr-able (-) - Polycythemia ... Vera (PV), Essential ... #Diagnosis #Algorithm
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Erythrocytosis) - Differential ... Diagnosis Algorithm ... • Burns • Diarrhea ... #Diagnosis #Algorithm ... #Causes #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Diagnosis Platelet ... Reactive: • Anemia/blood ... loss (Fe deficiency ... Thrombocythemia • Polycythemia ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... thrombocytosis • Polycythemia ... disorders • Celiac disease ... malignancy • Iron deficiency ... #Diagnosis #Algorithm
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Diagnosis Algorithm ... disorders (eg. polycythemia ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... - Differential ... Diagnosis Algorithm ... • Blood loss: ... conditions, Obesity, Polycythemia
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