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diagnosis algorithm causes syndrome blood chronic cll hemeonc hodgkins lad leukemia lymphadenopathy lymphocytic lymphoma monoclonal polycythemia product reactions treatment workup
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... Systemic histoplasmosis ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Lymphadenopathy - Differential ... Reactive: - Systemic ... Inflammatory • Systemic ... Algorithm #Causes #Hematology ... #Oncology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... • Gaucher's Disease ... Inflammatory • Systemic ... Spleen #Enlarged #Differential ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Congenital Diseases ... and Autoimmune Diseases ... : • Systemic lupus ... #Diagnosis #Hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Ig deposition disease ... Significance #MGUS #Differential ... #Diagnosis #hematology ... #oncology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Vascular System ... TeIangiectasia Vascular System ... Bleeding #Bruising #Differential ... Algorithm #Causes #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Chain deposition disease ... glomerulonephritis (>90%) S - Systemic ... Mnemonic #diagnosis #differential ... #hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Lymphadenopathy - Differential ... • Kikuchi Disease ... Lymphadenopathy #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... solid cancers • Systemic ... #diagnosis #management ... #treatment #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involvement Differential ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
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