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differential causes algorithm oncology hepatology management dermatology laboratory systemic chronic disorders generalized hepatitis lactate nephrology pathophysiology product pruritus reactions rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... deficiency • Fanconi’s anemia ... Cancer: • Leukemia ... erythematosus • HLH ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Chronic Myelogenous Leukemia ... Infectious: • Acute ... disorders • Celiac disease ... Iron deficiency anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Algorithm Blood ... Loss • Acute ... Disease • Marrow ... #Classification ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... , Liver diseases ... Malignant tumors, Acute ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... : Acute blood loss ... , deficiency anemia ... Vasculitides, IBD, Celiac disease ... #Differential #Diagnosis
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... the total white blood ... translocation • Acute ... Colitis and Crohn’s Disease ... #causes #hematology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... hepatomegaly and anemia ... Supportive with blood ... Hepatobiliary #hepatology ... #differential #diagnosis
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... chronic kidney disease ... , Acute blood loss ... #differential #diagnosis ... #causes #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Algorithm Acute ... CD13, CD33, CD34, HLA-DR ... Pelger-Huet, Macrocytic anemia ... #Disorders #hematology
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