12 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Anemia • Toxic Damage ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- APLS • Acute ... Scurvy - Actinic damage ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... infections • Tissue damage ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Infectious: • Acute ... disease Tissue Damage ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... #Causes #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... - ACS, AKI, acute ... signs of end organ damage ... diagnosis #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Mechanisms: • Direct Damage ... Constitutional Syndromes ... and petechiae Causes ... : - Genetic lesions ... Anemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
A quick infographic on the importance of sun protection and the various results of sun damage
#wavelengths #causes ... #diagnosis #dermatology ... Acute effects of ... Beane Freeman LE ... Genetic determinants
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Autoimmune (Sjogren, SLE ... chemotherapy) • Genetic ... syndromes (XMEN ... ICL #diagnosis #hematology ... #Differential #Causes