31 results
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... scale - Holster sign ... Dermatomyositis #Diagnosis #Rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... effusion, Restrictive lung ... Thrombocytopenia #Lupus #SLE ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... organ-specific signs ... Differential #diagnosis #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Anemia #diagnosis #management ... #treatment #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Myositis 4% - Lung ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs ... #differential #rheumatology
Metatarsal Gout on POCUS

Painful and swollen 1st metatarsal. Double contour sign. Diagnosis? Gout. 

Global Ultrasound Institute
Metatarsal Gout on POCUS ... Double contour sign ... Gout #Metatarsal #POCUS ... #clinical #rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
not be seen try focus ... migrans: • Target sign ... gabrieltalledop #dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology