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Anemias - Differential and Diagnostic Clues

Ariella Coler-Reilly @AriellaStudies

#Anemias #Differential #Diagnosis #Clues #Hematology
Differential and Diagnostic ... Clues Ariella ... #Differential #Diagnosis ... #Clues #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
- Differential Diagnosis ... Vesiculobullous #SkinRash ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... • Transfusion reactions ... #Differential #Diagnosis ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... deficiency • Liver ... fever • Drug reactions ... #hematology #rheumatology ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... effect following treatment ... #Algorithm #Causes ... #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... during an allergic reaction ... Or Inflammatory Reactions ... #Differential #Diagnosis ... #causes #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... Renal Disease, Liver ... #Algorithm #Causes ... #Hematology
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
Interpretation Reaction ... fibrin clot - Treatment ... interaction - Treatment ... Thromboelastography #diagnosis ... #coagulation #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... allergy, drug reaction ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia