25 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
skin/soft tissue infections ... more for MRSA bacteremia ... /endocarditis (due ... cidal nature) #Pharmacology ... #Antibiotics #Review
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Bug: Atypical bacteria ... Aggressive: MRSA bacteremia ... Immunocompromise Treatment ... lines, osteo, endocarditis ... • Secondary to Treatment
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... suspected (pneumonia, bacteremia ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
and sources of infection ... • Soft tissue infections ... for TPN) and antibiotic ... Sources #Causes #Bacteria ... #Microbiology #Diagnosis
Suspected catheter-related bloodstream infection - Management Algorithm
 • Temperature 37.8 C   • Rigors
Persistent fever and/or bacteremia ... (endocarditis, ... Persistent fever and/or bacteremia ... Hernodynamically stable after treatment ... Algorithm #CRBSI #diagnosis
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview

Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis
Spectrum: covers MRSA
Dalfopristin) (IV) - Antibiotics ... Poor choice for bacteremia ... /endocarditis due ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
lipoglycopeptide antibiotics ... ) - Antibiotics ... organisms, including bacteremia ... #Pharmacology #Antibiotics ... #Review #Overview
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
treat bacterial infections ... the growth of bacteria ... Imagine treatments ... and effective relief ... #Antibiotics #pharmacology
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... severe fungal infections ... (endocarditis, ... #Pharmacology #Antibiotics ... #Review #Overview
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Culture-Negative Infective Endocarditis ... Work-up of BCNIE relies ... BCNIE Diagnostic ... Negative #Infective #Endocarditis ... #diagnosis #differential