16 results
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Function Tests (LFTs ... Normal Values and Interpretation ... hepatocellular injury ... Function #Tests #LFTs ... #diagnosis #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis ... #differential #hepatology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Increased Serum bilirubin ... #Workup #Hematology ... #Diagnosis *
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
- Differential Diagnosis ... Algorithm Pre-Hepatic ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hepatology #bilirubinemia
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Chemistries - Interpretation ... of LFTs R-value ... liver #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
- Differential Diagnosis ... Algorithm 1. ... non-ICU vs ICU causes ... Hyperbilirubinemia #direct #bilirubin ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #differential #Diagnosis ... gastroenterology #algorithm ... gastroenterology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Algorithm Severe ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Algorithm #Causes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... Differential Diagnosis ... #Differential #Diagnosis ... #hepatology #algorithm ... Transaminitis #LFTs
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Increased Unconjugated Bilirubin ... #Algorithm #Causes ... #Hematology