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Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Features of hematologic ... B-symptoms, bruising/bleeding ... hepatomegaly • Labs: anemia ... #Leukocytosis #Differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... • Acute Bleed ... #Differential # ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Loss • Acute Bleed ... Smear • Chronic Bleed ... Classification #Approach #Differential ... Algorithm #Causes #Hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
CHA2DS2VASc vs HAS-BLED ... stroke risk and bleed ... S Stroke 1 B Bleeding ... history/anemia ... AFib #Diagnosis #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential ... Iron #Deficiency #Anemia ... #Differential # ... Algorithm #ferritin #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... 80-100 fL) • Bleeding ... Classification #Differential ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... - History of bleeding ... epistaxis, gingival bleeding ... menstrual - Recent procedures ... changes), high MCV anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Sideroblastic anemia ... Liver diseases, Bleeding ... key #diagnosis #differential ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
particular degree of anemia ... Index < 2: • Anemia ... loss: Trauma, Gl bleed ... Production #Index #hematology ... #anemia #differential
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... Blood Loss, Occult Bleed ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
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