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diagnosis differential management hematology hyperkalemia anemia nephrology potassium high cardiology criticalcare hepatology pathophysiology chloride classification clinical hba1c macrocytosis neurology product
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Thresholds in Critical ... blood is a liquid ... Blood saves lives ... unnecessary and cause ... #Thresholds #Hematology
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... turnover • Acute blood ... loss • Hemolytic
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... autoimmune (most of the causes ... , hemolytic transfusion ... Differential #Diagnosis #Causes ... #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... • Peripheral blood ... disease, drugs, transfusions ... Differential #Diagnosis #Algorithm ... #causes
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Febrile Non-Hemolytic ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Decreased WBCs ... - Decreased/NormaI ... Bleed • Hemolysis ... #Causes #Hematology
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... dietary intake • Blood ... transfusion • ... of injection Decreased
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... transfusion • ... - Transfusion ... Blood transfusion ... differential #diagnosis #causes
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic algorithm ... Decreased renal ... Potassium-rich diet • Blood ... transfusion • ... Tumor lysis/hemolysis
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