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differential anemia hematology hyperkalemia classification hemolysis bilirubinemia blood deficiency dm2 elderly elevation endocrinology extravascular falls false fe geriatrics hba1c hepatology
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Extrinsic Causes ... autoimmune (most of the causes ... , hemolytic transfusion ... #Diagnosis #Causes ... #Algorithm
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... HUS) • Other: Transfusion ... reaction • Intrinsic ... Extravascular #Causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Content • RBC Transfusions ... blood loss • Hemolytic ... Effect • RBC Transfusions ... #Decrease #Diagnosis
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Intrinsic Causes ... elliptocytosis Extrinsic ... prosthetic valve • Transfusion
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential Diagnosis ... Algorithm Hereditary ... disease, drugs, transfusions ... #Differential #Diagnosis ... #Algorithm #causes
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management
Causes of Falls in the Elderly - Differential Diagnosis Algorithm - Intrinsic Factors - Presyncope / Syncope
Causes of Falls ... Algorithm - Intrinsic ... • Weakness • Decreased ... Arthritis - Extrinsic ... #Algorithm #Causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... Algorithm Decreased ... WBCs - Decreased ... #Algorithm #Causes
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... diet • Blood transfusion ... • Tumor lysis/hemolysis ... #algorithm #nephrology
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased ... #Causes
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