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diagnosis differential management hematology neurology syndrome hyperkalemia pharmacology pulmonary reactions treatment adjusted age benefits blood bulimianervosa cardiology coagulation comparison complications
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation == Decreased ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... Cell Disease • Decreases ... number of pain crises ... 24%) • Fewer transfusions ... Benefits #SickleCell #pathophysiology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Hemolysis on labs ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Normal or slightly elevated ... Mild-to-moderate decrease ... in most cases; ... Platelet count - Decreased ... or may not be elevated
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... blood donor • Pathophysiology ... without other cause ... • Pathophysiology ... resp distress, elevated
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased ... Differential #Diagnosis #Causes
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology ICH Management: 1. Manage Blood Pressure •
Pressure (ICP) - Pathophysiology ... consider platelet transfusion ... = dilated BV = raises ... Hemorrhage #ICH #elevated ... Pressure #ICP #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Diuretics, PRBC transfusion ... Lysis Syndrome: • Pathophysiology ... , Elevated uric
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... fibrinogen • Elevated ... protein C and S Pathophysiology ... Treat primary cause ... hydration • RBC transfusion
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... intracellular calcium causes ... of the heart - Decreased ... levels can be elevated ... #Pharmacology #Pathophysiology
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