25 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... Proliferative Class IV ... #Classification ... #diagnosis #management ... #nephrology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... by 12 months Classification ... #Nephritis #Management ... #rheumatology #nephrology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... least 2 joints • Neurologic ... Delirium, Psychosis, Seizure ... nephritis, Class ... Ill or IV lupus
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... with systemic lupus ... > 500 mg/d • Nephritic ... algorithm #sle #nephrology ... #biopsy #indications
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Kidney Injury - Classification ... tubular necrosis (causes ... Acute interstitial nephritis ... tract infection • Medications ... #diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... • Drugs • HIV ... IgA, post-strep, lupus ... Acute Interstitial Nephritis ... #KidneyInjury #Nephrology
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
Proliferative Lupus ... Nephritis (Class ... (Euro-Lupus) 500 ... #Nephritis #management ... #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... mood disorder • Seizures ... • Psychosis • Seizures ... titers > 1:80 • CBC ... activation and/or medications
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Hypothyroidism • Medication-induced ... • Infectious: HIV ... Vasculitis, Sjogren's, Lupus ... differential #diagnosis #causes ... #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Movement disorders, Seizure ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management