22 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Differential Diagnosis Algorithm ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... Inflammatory • Systemic Lupus ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... • Secondary (e.g ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Chronic Disease (e.g ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Differential Diagnosis Algorithm ... Iron Deficiency (Eg ... Other • e.g ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Differential Diagnosis Algorithm ... Increased Requirement (e.g ... • Rule out B12 and ... #Causes #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL and ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... function test, ANA (e.g ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology