34 results
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Serotonin Syndrome • Ophthalmologic ... Diaphresis, flushing • CNS ... Serotonin #Syndrome #Symptoms ... #spectrum #signs ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus (SLE ... Normal CK - Myositis ... Erythematosus #SLE ... pathophysiology #signs ... #symptoms #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... pain • Extra-CNS ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... /full triad at diagnosis ... Can also see mechanics
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
Differential diagnoses ... for the neuro-ophthalmologic ... #Diplopia #Differential ... #Diagnosis #Causes ... #Ophthalmology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
anemia 4% - Myositis ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... pulmonary etc) • CNS ... Lack of UMN/LMN signs ... #Diagnosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Bilateral signs ... and/or symptoms ... Disorders: - SLE ... #neurology #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
symptoms (headache ... Behcet disease) Differential ... Oral aphthae : SLE ... inhibitors • Uveitis- Ophthalmology ... #management #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Glomerulonephritis Myositis ... Thrombocytopenia #Lupus #SLE ... erythematosus #signs ... #symptoms #diagnosis