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neurology rheumatology erythematosus lupus systemic autoimmune management myositis syndrome algorithm autoantibodies behcet cauda caudaequina causes complications cord disease disorders equina
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
Adie's Pupil What ... Young females Differential ... Diagnosis: • CN ... #Pupil #PhysicalExam ... #neurology #ophthalmology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Necrotizing myopathy ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... Can also see mechanics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Normal CK - Myositis ... femoral heads • Myopathy ... pathophysiology #signs ... #symptoms #diagnosis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... pulmonary etc) • CNS ... Lack of UMN/LMN signs ... #Diagnosis #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Bilateral signs ... and/or symptoms ... Disorders: - SLE ... #neurology #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
anemia 4% - Myositis ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... Diagnosis Framework ... and signs below ... - Transverse myelitis ... Behcet disease - SLE
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
symptoms (headache ... Behcet disease) Differential ... Oral aphthae : SLE ... inhibitors • Uveitis- Ophthalmology ... #management #signs
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... equina syndrome (CES ... Diagnosis: • ... • Transverse myelitis ... #diagnosis #causes
Photophobia and Headache - Differential Diagnosis Framework Why? • The coexistence of photophobia and headache suggests the potential
Diagnosis Framework ... - Autonomic symptoms ... meningeal irritation signs ... Trochlear headache • CNS ... #diagnosis #ophthalmology
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