111 results
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Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Other brainstem syndromes ... • Transverse myelitis ... pain • Extra-CNS ... Manifestations #diagnosis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... pulmonary etc) • CNS ... • Acute stroke syndromes ... Paraneoplastic syndrome ... #Differential #Diagnosis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal Syndromes ... - Differential Diagnosis ... Complement Levels: SLE ... , Inflammatory Myositis ... #Differential #Diagnosis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... LAC) • Sjogren Syndrome ... Peptide (CCP) • Myositis ... #Rheumatology #diagnosis ... #associations #table
Differential Diagnosis of Necrotizing Fasciitis: Cellulitis, Superficial abscess, Deep vein thrombosis (see phlegmasia cerulea dolerans), Compartment
Differential Diagnosis ... thrombosis (see ... Compartment syndrome ... Necrotizing myositis ... #Differential #Diagnosis
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... Chorioretinitis • Diagnosis ... - Compatible syndrome ... nodules, may also see ... #differential #diagnosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... #CNS #neurology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... anti-synthetase syndrome ... /full triad at diagnosis ... Can also see mechanics ... #diagnosis #rheumatology
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