18 results
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... - Clinical Presentation ... • Bilateral signs ... Disorders: - SLE ... #neurology #differential
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... TIF1y, NXP2, Mi-2, SAE ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Beevor's Sign on Physical Exam

Beevor's sign is abnormal upward (cephalad) movement of the umbilicus with truncal
Beevor's Sign on ... paralysis from spinal cord ... inclusion body myositis ... PhysicalExam #clinical ... video #umbilicus #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... pulmonary etc) • CNS ... of the spinal cord ... Lack of UMN/LMN signs ... #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... pain • Extra-CNS ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... ) Clinical Manifestations ... #CNS #neurology ... #rheumatology #
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential Diagnosis ... : CHF, valves, COPD ... Rhabdomyolysis, Critical ... body-), PMR, RA, SLE ... #causes #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... • Symptoms and signs ... - Transverse myelitis ... Behcet disease - SLE ... #neurology #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Systemic Lupus (SLE ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... matter, spinal cord ... Oral aphthae : SLE ... #management #signs ... #symptoms #rheumatology