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diagnosis differential anemia aflp autoimmune cold criticalcare dermatology extravascular hellp hemolysis intravascular obstetrics pharmacology pregnancy thrombocytopenia ttphus aiha allergy burns
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Immunosuppression, Splenectomy Cold ... BostonChiefs #Warm #Cold ... #Anemia #hematology ... #diagnosis #comparison
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... Warm AIHA • Cold ... Complement-Mediated • Cold ... #Causes #Hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... AIHA (48-70%) Cold ... HA (paroxysmal cold ... hemoglobinuria) • Cold ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... Extravascular #Causes ... differential #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... • AIHA: warm, cold ... udaygulati #Hemolytic ... #classification ... #hematology
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Differential Diagnosis Algorithm ... Artery Disease • Stable ... • Asthma • COPD ... Pneumonia • ARDS • COPD ... #Causes
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Agglutination - Cold ... Differential #Diagnosis #Algorithm ... #workup #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Cold Urticaria Prevalence ... skin contact with cold ... minutes after the cold ... 10.1111/all.14674 #Cold ... #comparison #table
Shock - Differential Diagnosis by Classification Hypovolemic (Intravascular volume depletion) - Hemorrhagic • Trauma
Differential Diagnosis by Classification ... Anaphylaxis - Spinal cord ... exacerbation (any cause ... Differential #Diagnosis #Classification ... #Table #CriticalCare
Causes of Pulmonary Hypertension - Differential Diagnosis Algorithm Pulmonary Arterial Hypertension • Idiopathic • Associated with:
Causes of Pulmonary ... Differential Diagnosis Algorithm ... Hypoxemia: • COPD ... Miscellaneous: • Hematologic ... #Causes
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