6976 results
differential clinical algorithm management causes cardiology pocus radiology physicalexam sign pulmonary neurology video pathophysiology ultrasound table comparison symptoms pediatrics peds
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in one cell ... mutated in all cells ... Retinoblastoma Signs ... ophthalmology #diagnosis ... #signs #symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... Physical Exam/Signs ... Diagnosis: • ... or basket cells ... Lymphocytic #Leukemia #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
B and CD-4+ T cells ... CRP Neuronal cell ... surface targeted -> Cell ... pathophysiology #diagnosis ... #signs #symptoms
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... yrs old; F>M Signs ... Anemia - Giant cells ... Pathophysiology #Diagnosis ... #Signs #Symptoms
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... Signs of immunodeficiency ... involved in B cell ... -> Impaired B cell ... humoral immunity Signs
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma Diagnosis ... Summary Clinical Signs ... pathologic fx) Diagnosis ... marrow plasma cells ... plasma clonal cell
Antiphospholipid Syndrome (Hughes' Syndrome) Antiphospholipid syndrome - an autoimmune condition where the affected individual produces antibodies
antibodies against cell ... Syndrome #APLS #Signs ... #Symptoms #Diagnosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Giant Cell (Temporal ... Complications Signs ... Complications #Signs ... #Symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... UV light Incr cell ... removal of these cells ... pathophysiology #diagnosis ... #signs #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
commonly hairy-cell ... vascular endothelial cells ... Pathophysiology #Diagnosis ... #Signs #Symptoms
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