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diagnosis hematology causes algorithm neurology anemia cardiology oncology classification endocarditis endocrinology infectiousdiseases nephrology signs symptoms thrombocytopenia chronic criticalcare erythematosus fever
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... disease • vWF ... #treatment #hematology ... #differential
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... methotrexate) • Drugs Autoimmune ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... microsomal) - Autoimmune ... - Vasculitis, e.g ... - Vasculitis, e.g ... diagnosis #table #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... Extravascular #Causes #differential
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Short Stature - Differential ... • Cushing's Disease ... Panhypopituitarism Treatment ... Transplant Chronic Disease ... • GI (e.g.
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
mild to severe, Colour ... (e.g. oculomotor ... (AQP4-lgG disease ... ; e.g. narcolepsy ... Myositis, Comorbid autoimmune
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Origin (FUO) - Differential ... Infected thrombosis, (e.g ... Lemierre's syndrome ... (e.g. autoimmune ... #Origin #FUO #Differential
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Malabsorption - Differential ... Cholestatic drugs- e.g ... Shwachman-Diamond syndrome ... • Short bowel syndrome ... Malabsorption #Differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... EBV infection, Autoimmune ... diseases (e.g., ... Malignancies (eg ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... inflammatory disorders (e.g ... . autoimmune, TB ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
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