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diagnosis differential algorithm cardiology chf clinical hfref management photo anemia arterial basophilia basophils drugrelated embolism exanthema ferritin flexural gangrenosum guidelines
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... malignancy • Iron ... deficiency anemia ... #Hematology
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Iron Deficiency ... ng/mL (absolute ID ... 20% (functional ID ... HF with iron deficiency ... #HFrEF #heartfailure
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... → Inflammation causes ... ng/mL (absolute ID ... 20% (functional ID ... #HFrEF #heartfailure
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Tropical sprue, IBD ... , Copper deficiency ... #Deficiency #Anemia ... Algorithm #ferritin #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Ulcerative Colitis and Crohn ... Chickenpox Other Causes ... : • Iron deficiency ... Differential #Diagnosis #causes ... #hematology #basophils
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Protein S deficiency ... - Protein C deficiency ... Ischemic Liver, IBD ... coagulation and other causes ... pathophysiology #hematology
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Gangrenosum (PG) 50 M Crohn ... conditions such as IBD ... -1β, IL-8, IL-17 ... medications in most cases ... clinical #photo #dermatology
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
+burning rash groins ... warm,red patch groins ... MCQ highlights a case ... Washington University ID ... clinical #photo #dermatology
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