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diagnosis differential algorithm clinical dermatomyositis management photo rheumatology thrombocytosis thrombosis venous anemia antimda5 antimda5dm antinxp2 antinxp2dm clots cutaneous dermatologic dermpath
Dermatologic Extraintestinal Manifestations in IBD - IBD Algorithm Erythema Nodosum Pyoderma Gangrenosum Metastatic Crohn's Disease Sweet Syndrome EBA Dr. Wade Billings @wabillin #Dermatologic
Manifestations ... in IBD - IBD Algorithm ... Gangrenosum Metastatic Crohn's ... #IBDAlgorithm #IBD ... gastroenterology #management #dermatology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... Lipoprotein a ↑ - IBD ... APLS:PLT ↓ HEMATOLOGIC ... Diagnosis #clots #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... malignancy • Iron deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Protein S deficiency ... - Protein C deficiency ... Ischemic Liver, IBD ... coagulation and other causes ... pathophysiology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Acute hemolysis, deficiency ... Vasculitides, IBD ... infections, TB, Acute bacterial ... Diagnosis #Algorithm #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Tropical sprue, IBD ... Bypass surgery, Bacterial ... , Copper deficiency ... Algorithm #ferritin #hematology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... 2%) • Other: IBD ... Vasculitis #dermpath #dermatology ... diagnosis #clinical #manifestations
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous manifestations ... the disease and ILD ... increases and ILD ... prevalence of RP-ILD ... #dermatology #diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
targeting NXP-2 Manifestations ... Muscle atrophy may cause ... Dermatomyositis: • ILD ... • In severely ill ... #dermatology
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Gangrenosum (PG) 50 M Crohn ... conditions such as IBD ... -1β, IL-8, IL-17 ... medications in most cases ... clinical #photo #dermatology
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