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diagnosis differential algorithm management arterial blood clinical dermatomyositis photo product reactions skin thrombocytosis thrombosis venous anemia antimda5 antimda5dm antinxp2 antinxp2dm
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... malignancy • Iron deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... Acute hemolysis, deficiency ... Vasculitides, IBD ... Diagnosis #Algorithm #hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... Sarcoidosis • Crohn's ... gangrenosum • IBD ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... Lipoprotein a ↑ - IBD ... APLS:PLT ↓ HEMATOLOGIC ... Diagnosis #clots #hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Hemophilia A - Deficiency ... Hemophilia B - Deficiency ... celiac disease, CF, IBD ... comparison #diagnosis #hematology ... #deficiency
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Tropical sprue, IBD ... Zinc excess or deficiency ... , Copper deficiency ... Algorithm #ferritin #hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... Tamponade Pulmonary Causes ... • Parenchyma: ILD ... syndrome Other Causes ... Transverse myelitis • Hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
the disease and ILD ... increases and ILD ... prevalence of RP-ILD ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Ulcerative Colitis and Crohn ... Chickenpox Other Causes ... : • Iron deficiency ... Differential #Diagnosis #causes ... #hematology #basophils
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Protein S deficiency ... - Protein C deficiency ... Ischemic Liver, IBD ... coagulation and other causes ... pathophysiology #hematology
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