18 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... APS), Secondary prevention ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... incidentally via CBC ... of symptoms and prevention ... PV #Diagnosis #Management ... #hematology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
particularly underlying renal ... • Treatment includes ... prevention by minimizing ... toxicology #diagnosis #management ... #nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Anaphylaxis, Acute Renal ... APML #diagnosis #management ... #hematology #oncology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... or 0.5 g/day → renal ... #treatment #management ... #rheumatology # ... nephrology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... bradycardia, urinary retention ... Treatment: • Plasmapheresis ... Syndrome #diagnosis #management ... #treatment #neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Bleeding (64%) • Renal ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... irrigation • Management ... nocturnal enuresis • Prevention ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Immunosuppressive agents, Renal ... Etiology: • Pathophysiology ... Syndrome #diagnosis #management ... #neurology