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diagnosis differential hypercoagulable syndrome workup amyloid amyloidosis antiphospholipid apls aptt bleeding bruising cryofibrinogenemia dermatology dic disseminated hepatology hepatorenal hrs intravascular
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... Rare • Drugs (e.g ... #Algorithm #Causes ... #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Prolonged Activated Partial ... Jcortesizaguirr #Abnormal ... #diagnosis #differential ... #hematology #coagulation
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
Hypercoagulable State Arterial ... rhythm monitoring, Echocardiogram ... • Provoked (e.g ... #diagnosis #algorithm ... #hematology #VTE
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
variants of both • Acral ... Treat primary cause ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm Face • Melasma Abdomen • Linea Nigra Hormone induced
- Differential Diagnosis ... Algorithm Face ... Distensae (striae ... #SkinChanges #normal ... #Algorithm #causes
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
• Caused by splanchnic ... • ↓ Effective arterial ... • Normal kidney ... Exclude other AKI causes ... liver insult (e.g
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cooled from the normal ... cryoglobulin (CG ... including retinal arterial ... cryoglobulins • Negative causes ... hematology
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
LVH, low-voltage EKG ... hypoadrenalism • Nausea ... • Echocardiogram ... Doppler imaging: Normal-size ... disproportionate atrial
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup Algorithm ... clinical episodes of arterial ... maternal chromosomal causes ... Hypercoagulable #Workup #Algorithm ... #diagnosis #hematology
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