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differential obstetrics pregnancy causes coagulation comparison hellp blood classification dic disseminated laboratory obgyn reactions table thrombocytopenia ttphus abnormal activation anemia
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... acid metabolism products ... rapidly develops (DIC ... iMedEducation #AFLP ... Pregnancy #hepatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... schistocytes, DIC ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
for Disseminated Intravascular ... Elevated as this is a product ... #Disseminated #Intravascular ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Hemolysis, Elevated Liver ... schistocytes, DIC ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
of Pregnancy (AFLP ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... #differential #diagnosis ... #icp #HELLP #AFLP
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... Extrinsic Causes: • Liver ... IVIG infusion Intravascular ... MAHA: TTP, HUS, DIC ... classification #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
- Thalassemia, Liver ... , Disseminated intravascular ... coagulopathy (DIC ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Severe Liver ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... of fibrin-split products ... As a result of DIC ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Disseminated intravascular ... coagulation (DIC ... Prolonged #Causes #diagnosis ... #differential #hematology
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