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differential aflp obstetrics pregnancy thrombocytopenia comparison hemolysis causes liver obgyn ttphus algorithm anemia common cvid disease extravascular fatty framework hemolytic
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Syndrome and Acute ... Pregnancy (AFLP) Three syndromes ... schistocytes, DIC ... AFLP #obstetrics #hematology ... #diagnosis #table
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... transplant • DIC ... hemolytic anemia" • HELLP ... #hematology #hemolysis
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... schistocytes, DIC ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Non-lmmune: • HELLP ... Syndrome • TTP ... /HUS • DIC • ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
- Differential Diagnosis ... Microangiopathy: DIC ... antiphospholipid syndrome ... - Pregnancy: HELLP ... #Framework #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... MAHA: TTP, HUS, DIC ... , HELLP - Grafts ... Drug-associated, PCH, Evans Syndrome ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation (DIC ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... #hematology #anemia
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
, no necrosis HELLP ... Syndrome (Hemolysis ... Disease #Pregnancy #hepatology ... #differential #diagnosis ... #icp #HELLP #AFLP
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
rapidly develops (DIC ... ) Differential Diagnosis ... Preeclampsia, HELLP ... Liver #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and M panel Management ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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