40 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... Treatment: • Consider ... (transfusions, antibiotics ... diagnosis #management #treatment ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelofibrosis Infectious ... Non malignant hematologic ... effect following treatment ... states • Non-hematologic ... Iron deficiency anemia
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... Class Overview ... adverse effects = Hematologic ... #Pharmacology #Antibiotics ... #Review #Overview
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... hemolysis, deficiency anemia ... Rebound effect from treatment ... : Chronic infections
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Overview Who ... - β-lactam antibiotics ... Idiopathic • Infections ... Treatment: ... #oncology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... Drugs (Beta lactam antibiotics ... spherocytosis) • Infections ... differential #diagnosis #hematology ... #anemia
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Autoimmune Hemolytic Anemia ... (AIHA) Treatment ... Polyclonal: - Infection ... #AIHA #Treatment ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
CLL) - Summary Overview ... 5) Symptoms of anemia ... Complications: 1) Infection ... marrow failure with anemia ... Leukemia #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... risk-stratification • Risks: infection ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... predictive of a serious infection ... overlook severe infections ... superior indicator of infection ... neutrophil #WBC #CBC #hematology