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diagnosis management disease erythematosus joint lupus oncology pain signs sle symptoms workup anemia arthritis classification dermatology msk product reactions syndrome
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... pain (20%) Renal disease ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad: Fever ... fraction < 20% Differential ... solid cancers • Systemic ... management #treatment #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Neurologic system ... Genitourinary system ... arteritis • Bloody ... #joint #pain #differential ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis: • Fevers ... purpura: strong sign ... pulses, bruis, or blood ... Large Vessel: Blood ... #diagnosis #rheumatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
Diagnostic Approach and Differential ... dullness, puddle sign ... incisional). 3) Signs ... of underlying disease ... #Diagnosis #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
long (in days) it takes ... the peripheral blood ... Chronic kidney disease ... Production #Index #hematology ... #anemia #differential
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... disease. ... Episcleritis Signs ... , breast CA - Hematologic ... neutrophils in the blood
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis: • Fevers ... purpura: Strong sign ... pulses, bruits, or blood ... #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... to: Arthritis, Fever ... Erythematosus #Diagnosis #Rheumatology
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