1225 results
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... Cell Disease • Decreases ... 4.5 vs. 2.4) • Decreases ... organ benefit and decreased ... Benefits #SickleCell #pathophysiology
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
limbic circuitry -> Decreased ... SAM) pathway -> Decreased ... Thyroid Activity -> Decreased ... thyroid activity -> Decrased ... Differential #Diagnosis #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Excretion Decreased ... , Pentamidine Decreased ... Ketoconazole Decreased ... Beta-Blockers Decreased ... #Hyperkalemia #Pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Factors (GF's) • Decrease ... Bone Resorption, Decreased ... #Osteoporosis #pathophysiology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Cardiovascular disease -> Decreased ... , Diuretics -> Decreased ... #Pharmacology #Pathophysiology
Conceptual Relationship between Volume Responsiveness and Volume Tolerance

Assessing for volume responsiveness would only tell you that
"Left Shift" (Decreased ... glycocalyx damage -decreased ... oncotic pressure -decreased ... #Differential #Pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
gland size - Decreased ... (Dry eyes) - Decreased ... Dry Mouth) - Decreased ... Nocturnal cough - Decreased ... Sjogrens #Syndrome #Pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Left Shift - decreased ... tissue level (i.e. decreased ... Dissociation #Curve #Pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... ferroportin → Decreased ... ferroportin leads to decreased ... symptoms and QOL and decreased
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
This decreases secondary ... #Pharmacology #Pathophysiology