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hematology signs management hemolytic oncology algorithm workup causes classification erythematosus lupus sle systemic arthritis hemolysis hemophagocytic hlh hodgkins leukemia lymphohistiocytosis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... Signs of anemia ... #Differential # ... #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • Membrane defects ... Causes: • Liver disease ... , spider/snake bites
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... #Differential # ... #workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... , Drugs, Liver Disease ... : Sickle cell anemia ... #Diagnosis #hematology
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
- Diagnosis Algorithm ... suspected: • Signs ... and symptoms of ... Iron-deficiency anemia ... microscopic colitis Differential
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... , neural tube defects ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Intrinsic RBC Defects ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Restrictive lung defect ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... #Diagnosis #hematology ... #rheumatology #
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