11 results
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Excretion Effects ... Diuresis, Na+, ... Carbonic Anhydrase Inhibitor ... #effects #pharmacology ... #comparison #table
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Mechanism of Action, Effects ... CARBONIC ANHYDRASE INHIBITORS ... others SGLT2 INHIBITORS ... #Medications #Pharmacology ... #summary #table
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Proton-pump inhibitors ... Renal Loses - Medications ... - Uncontrolled diabetes ... - Genetic defects ... Low #Magnesium #Table
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
Effects on body ... classes of type-2 diabetes ... Loss + - SGLT-2 inhibitors ... Loss +++ - DPP-4 inhibitors ... weightgain #comparison #pharmacology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... drugs include side effects ... are similar to diuretics ... Side effects include ... #Pharmacology #
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... failure Common Side Effects ... definitively cause/effect ... #Pharmacology # ... Summary #DM2 #diabetes
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Nephrogenic diabetes ... Lithium-induced nephrogenic diabetes ... DDAVP) • Central diabetes ... #Nephrology #Pharmacology ... #Medications #Table
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... leading to osmotic diuresis ... ) Common Side Effects ... #Pharmacology # ... Summary #DM2 #diabetes
SNRls (Serotonin/Norepinephrine Reuptake Inhibitors) - FDA Approved Indications 

Venlafaxine (Effexor) - GAD, MDD, Panic Disorder, SAD
Norepinephrine Reuptake Inhibitors ... Cymbalta) - GAD, MDD, Diabetic ... Serotonin-Norepinephrine Reuptake Inhibitors ... hypertension due to the effects ... #Pharmacology #
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... • Dehydration: Diuretics ... NSAIDs, calcineurin inhibitors ... anticholinergic effects ... #Drugs #pharmacology