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diagnosis causes algorithm hematology cardiology infectiousdiseases management pathophysiology rheumatology secondary systemic workup approach arthritis classification dermatology disorders orthopedics pulmonary thrombocytosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... blood loss), Vitamin ... deficiencies: Chronic ... > 3: • Acute blood ... #differential #
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , Chronic disease ... Chemotherapy (e.g ... disease, McLeod blood ... RBC #Morphology #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... of Chronic Disease ... (e.g. ... Classification #Differential
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm Blood ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Classification #Approach #Differential
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... Causes: Chronic ... Blood Loss, Occult ... #elevatedMCV #Differential
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Diet: ↓ Intake, e.g ... , Menorrhagia, Blood ... Inflammation: IBD, Chronic ... Deficiency #Causes #differential ... #diagnosis #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... • Secondary (e.g ... RA, SLE, PRV, Chronic ... #Differential #
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
of chronic inflammation ... of chronic kidney ... disease, Acute blood ... chronic inflammation ... morphologic #mcv #differential
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Reactive: • Anemia ... /blood loss (Fe ... Myelofibrosis • Chronic ... Thrombocytosis #Differential
Oxyhemoglobin Dissociation Curve Left Shift - decreased unloading of O2 at tissue level (i.e. increased
• stored red blood ... pregnancy • chronic ... anæmia ... - Sickle cell anemia ... #Right #Shift #Differential
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