29 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... lymphocytic lymphoma (SLL ... Lymphocytic Lymphoma (SLL ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute leukemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Leukemia, Tumour ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Non-Infectious: • Rheumatologic ... : SLE, Rheumatoid ... Arthritis, Sjogren Syndrome ... Disease, Behcet Syndrome ... Primary: Lymphoma, Leukemia
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... block • Sjogren syndrome ... polymyositis overlap syndrome ... • Specific for SLE ... Summary #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... Oral aphthae : SLE ... tears, Ischemia, Leukemia ... • Arthritis: SLE ... signs #symptoms #rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Special cases (e.g. renal ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels
Causes of Anterior Uveitis - Differential Diagnosis
Anterior Uveitis - 90% of cases of Uveitis
 • Inflammation
Posner-Schlossman Syndrome ... Inflammatory: Behcet's, SLE ... , TINU syndrome ... (w/ renal involvement ... : Malignancy - Leukemia
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Hodgkin lymphoma and leukemia ... Erythematosus #Diagnosis #Rheumatology