93 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... severe disease & renal ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(Clinical Dx). ... Oral aphthae : SLE ... • Arthritis: SLE ... diagnosis #management #signs ... #symptoms #rheumatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN) - See Updated MP4 Clip Here: https://www.grepmed.com/images/6837

Nikolsky's sign is
Necrolysis (TEN) - See ... is a clinical dermatological ... Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... #Video #Clinical
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Clinical Manifestations ... of Serotonin Syndrome ... Cardiovascular and ... vital sign abnormalities ... Akathisia, Altered Mental
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Systemic Lupus (SLE ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... concentration: > 750ng/mL and ... Special cases (e.g. renal ... #rheumatology # ... pharmacology #levels
Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the
Raynaud's Syndrome ... #Raynauds #Syndrome ... disease #phenomenon #clinical ... #video #physicalexam ... fingers #hands #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... is clinically suspected ... overlap syndromes ... erythematosus #diagnosis #rheumatology ... #table #ANA
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
is a clinical dermatological ... Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... #PhysicalExam #Video ... #Clinical #SJS