37 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Angiotensin-converting enzyme (ACE) inhibitors ... • Calcineurin Inhibitors ... #hyperkalemia #differential ... #diagnosis #pathophysiology
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
Check point inhibitors ... of check point inhibitors ... to months after treatment ... the checkpoint inhibitor ... AdverseEffects #Oncology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... the first-line treatments ... inhibits PTH release ... #Pharmacology #Pathophysiology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
the Rash in a an oncology ... Gangrenosum, NEH T - Treatment ... #skin #Rash #oncology ... #differential #
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... inducers (↑) and inhibitors ... concentrations, and inhibitors ... by inducers or inhibitors ... #Chemotherapy #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
transformation) Treatment ... AIHA, PRCA) • Treatment ... (Bruton kinase inhibitor ... Venetoclax (BCL2 inhibitor ... Lymphocytic #Leukemia #oncology
Dyspnea - Considerations with Malignancy
Directly Malignancy Related:
 - Lymphangitic spread to lung
 - Malignant pleural effusion
metastases Treatment ... dyspnea #algorithm #differential ... #diagnosis #oncology
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Anemia #Causes #Pathophysiology ... #Pathology #Treatment ... #Management #Differential
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... Renal Failure Treatment ... management #hematology #oncology