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differential management hemolytic algorithm oncology causes workup syndrome autoimmune intravascular atlas blood chronic cll cold extravascular hemeonc leukemia lymphocytic morphology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... • Extrinsic RBC ... • Intrinsic RBC ... #hematology
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
Pathophysiology ... of Hemolytic Anemia ... - Defects in RBC ... #Hemolytic #Anemia ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Pathophysiology, Signs and Symptoms of Hemolytic Anemia #Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, ... and Symptoms of Hemolytic ... Anemia #Pathophysiology ... #Hemolytic #Anemia ... #hematology #diagnosis
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... ↑ LDH • Anti-RBC ... #Anemia #diagnosis ... #management #treatment ... #rheumatology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Spherocytes • Treatment ... • Treatment: Warm ... #Anemia #hematology ... #diagnosis #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... • Intrinsic RBC ... #differential #diagnosis ... #hematology #anemia
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... Asplenism, Severe hemolytic ... , Hemolytic anemia ... Inclusions #Bodies #diagnosis ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... elliptocytosis - RBC ... anemia • ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Defects: Sickle cell anemia ... #Differential #Diagnosis ... #hematology
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