60 results
Von Willebrand Disease - Clinical Presentation, Diagnosis and Management

- Dr. Eric Strong @DrEricStrong - Strong Medicine
Von Willebrand Disease ... Presentation, Diagnosis ... and Management ... #Diagnosis #Management ... #hematology #treatment
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Hypersensitivity vasculitis ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... , Vasculitides, ... IBD, Celiac disease ... #Algorithm #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... permeability Diagnosis ... CNS #neurology #rheumatology ... #management #treatment
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
- Diagnosis, causes ... and management ... neuropathy Treatment ... with refractory disease ... #Rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... life-threatening • Treatment ... Evolution: Chronic disease ... Erythematosus #Diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... inflammation Others: • Lupus ... such as systemic lupus ... Presentation - Systemic Symptoms ... #rheumatology #