158 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Seronegative Reactive Syndrome ... fracture - Patellar dislocation ... Effusions: - Hematologic ... #diagnosis #msk
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
• Light-near dissociaton ... Holmes-Adie Syndrome ... Young females Differential ... no light-near dissociation
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Vascular Joint Pain - Differential ... Trauma to Vessel (dislocation ... Marfan's Syndrome ... Vascular #JointPain #MSK ... #Differential #
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... #Jaundice #Differential ... Algorithm #Causes #Hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... • Nonmalignant hematologic ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential
Isolated Hyperbilirubinemia - Differential Diagnosis Algorithm
Direct Hyperbilirubinemia: Dubin-Johnson Syndrome, Rotor Syndrome
Indirect Hyperbilirubinemia: 
 - Trauma, Hematoma,
Hyperbilirubinemia - Differential ... Dubin-Johnson Syndrome ... , Rotor Syndrome ... Hyperbilirubinemia #Isolated #Differential ... Diagnosis #Algorithm #hepatology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
hemolytic uremic syndrome ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... anemia" • HELLP syndrome ... #schistocytes #differential ... #diagnosis #hematology
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
Late Budd-Chiari syndrome ... Early Budd-Chiari syndrome ... leak, Nephrotic syndrome ... albumin #gradient #hepatology ... #differential #
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
Pupillary Defects - Differential ... Syphilis (light-near dissociation ... Midbrain (Parinaud's Syndrome ... Pupils #Defects #Differential