23 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Smith, Sm/RNP, Scl ... -7, PL-12, MDA5, ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ANA ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Smith, Sm/RNP, Scl ... • Fibrillarin, RNA ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - Differential ... Diagnosis Table ... (48-70%) Cold AHA ... #Diagnosis #Table ... #hematology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Ann Marie Kumfer ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
: Proximal and distal ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology # ... table
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
significant • Pattern ... : The ANA patterns ... Patterns and Associated ... #patterns #rheumatology ... #diagnosis #differential
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... rates of morbidity and ... mortality, and ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... Disease Associations ANA ... syndrome Anti-Scl ... Associations #diseases #diagnosis ... #table #rheumatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis - Differential ... Diagnosis Algorithm ... Cold AIHA • PCH ... #Diagnosis #Algorithm ... #Causes #Hematology