81 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Antibiotics Class Overview ... Rapidly cidal drug ... gram negative activity ... cidal nature) #Pharmacology ... Antibiotics #Review #Overview
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic Acidosis - Overview ... with exercise/activity ... Utilization (VO2) • Drugs ... Acidosis #types #differential ... #diagnosis #pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Antibiotics Class Overview ... positive agent with activity ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... Anemia • Hapten (Drug ... Omeprazole, Sulfa drugs ... Hemolytic #Anemia #differential ... #diagnosis #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Faget Sign - Pulse-Temperature Dissociation
Causes of Relative Bradycardia
 • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Pulse-Temperature Dissociation ... Factitious fever, Drug ... #Temperature #Dissociation ... #bradycardia #differential ... #diagnosis #causes
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Algorithm Pathophysiology ... anti-convulsant or sulfa-drug ... Immunocompromised #Diagnosis ... Targetoid #Algorithm #Differential
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Oxyhemoglobin Dissociation ... Oxyhemoglobin #Dissociation ... #Curve #Pathophysiology ... #Right #Shift #Differential ... #Causes #Diagnosis
Delirium Overview

 • What is Delirium?
 • Types of Delirium
 • Common Causes
 • Reversible Causes
Delirium Overview ... Reversible Causes • Drug-Induced ... #Delirium #diagnosis ... #management #differential