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diagnosis management differential rheumatology neurology algorithm hepatology cardiology dermatology infectiousdiseases signs symptoms anemia nephrology workup classification microscopy pediatrics physicalexam pulmonary
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... (e.g. autoimmune
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... microsomal) - Autoimmune ... - Vasculitis, e.g ... - Vasculitis, e.g ... diagnosis #table #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune ... disease • vWF ... #hematology #differential
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
• Cushing's Disease ... Panhypopituitarism Treatment ... Transplant Chronic Disease ... • GI (e.g. ... endocrinology #causes
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... , Etc. ... spherocytosis, Autoimmune ... Agglutinate: Cold autoimmune ... differential #diagnosis #hematology
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Causes of Fat Malabsorption ... Cholestatic drugs- e.g ... Shwachman-Diamond syndrome ... • Short bowel syndrome ... Differential #Diagnosis #Causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... for alternative causes ... Alcohol-related liver disease ... vascular disorder (e.g ... steatosis • Autoimmune
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... inflammatory disorders (e.g ... . autoimmune, TB ... Myelodysplastic syndrome ... #hematology #secondary
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