24 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
PT - Prolonged aPTT ... PT - Prolonged aPTT ... Coagulation #Abnormal #APTT ... #Laboratory #Hematology ... #Diagnosis #Workup
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
GI. uterine) Laboratory ... INR • Normal aPTT ... VonWillebrand #Disease #Diagnosis ... #Hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... thematttsai #PT #PTT ... Thromboplastin #laboratory ... #hematology #diagnosis
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
• Provoked (e.g ... screening, CBC, aPTT ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Prolonged PT and aPTT ... the PT and the aPTT ... Prolonged #Causes #diagnosis ... #differential #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... may prolong the aPTT ... Prolonged #Causes #diagnosis ... #differential #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
aggregation PT, aPTT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
- Differential Diagnosis ... • Infection (e.g ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #Oncology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
a clinical and laboratory ... diagnosis, not ... count, D-dimer, egg ... hemolytic #anemia #Hematology